What Dosage of CBD Should You Take?

CBD Dosage: What’s the Right Dose of CBD for Pain Relief?

What Dosage of CBD Should You Take?

Take a look at the label on any over-the-counter pain reliever and you can easily figure out how much you’re supposed to take for your symptoms. Finding the right dose of cannabidiol (CBD) for pain relief, however, isn’t that simple.

Enthusiasts rave about CBD’s potential to ease pain, reduce inflammation, relieve anxiety and promote sleep. However, there’s no conclusive research about just how much CBD a person needs to take in order to experience benefits.

There are very few human studies on CBD, and those that have been done include doses that are all over the map: In some studies, patients used 5 mg of CBD; in others, they took as much as 600 mg.

To further add to the confusion, CBD comes in a number of forms — oils and tinctures, creams and lotions, pills, vaping, and edibles — and each one has differences in terms of bioavailability (the percent of active ingredient that gets into your bloodstream).

“There are no standard doses for patients,” says Rachna Patel, DO, a physician who does consultations about medical marijuana and CBD and sells her own line of CBD products. “Ultimately, it’s trial and error, but you have to go about it in a methodical way.”

Here are some tips to guide you on how to find the right CBD dosage for your pain relief and other symptoms.

1. Work with an expert

Many factors, such as your body mass index (BMI), specific health condition(s) you have, medications you take, your health history, and the form of CBD you plan to use can influence how much CBD you may need to treat your symptoms. Although CBD is different than medical marijuana — which contains CBD as well as THC, an intoxicating ingredient — a doctor who’s well-versed in cannabis (marijuana) is probably the best person to help you help you sort it out.

“I wouldn’t recommend starting CBD without the supervision of a physician,” says Dr. Patel, author of The CBD Solution. “Many times people purchase a CBD product, try a dose that that doesn’t work for them, switch products and spin their wheels. Or, worse, they develop side effects.”

Ask your rheumatologist or primary care provider to recommend an expert, or find an expert near you by searching the directory of members of the Society of Cannabis Clinicians or the database maintained by your state’s medical marijuana program (if it has one).

2. Do some math

Let’s say you and your doctor settle on a dose of 30 mg of CBD per day. Now what? The answer depends on which form of CBD you take.

Figuring out how much CBD is in capsules or gummies is simple — just read the supplement facts section on the label. (If it says 10 mg of CBD per capsule, you’d take three capsules to get your 30 mg of CBD a day.)

Oils and tinctures can be trickier because the packaging often states the amount of CBD in the entire bottle, not in a dropper. This calculator can help you figure out how many drops you need the strength of the product.

When it comes to CBD in topical form (creams, lotions, and salves), you’ll probably see the total amount of CBD in the container listed on the label.

You’ll then have to divide that total by the number of millimeters in the package to determine how much is in each milliliter. For example, if you have a 50 ml jar of salve that contains 200 mg of CBD, there’s 4 mg per ml.

You should then use a metric measuring spoon to scoop out 7.5 ml to get a 30 mg dose of CBD.

3. Expect some trial and error

No two patients respond to CBD in the same way. You and your doctor will probably need to adjust the dose either up or down until you hit the right balance of benefits without side effects. “A lot of it depends on your biochemistry and the way your liver breaks down these chemicals. There’s a wide variety of factors that come into play,” says Dr. Patel.

It can take a little while to get it right, so be patient. Many people do not see a difference in symptoms after one or two doses of CBD.

It can take up to eight weeks of regular use to feel an impact, says Bridget Seritt, co-founder of the Canna-Patient Resource Connection, a Colorado-based organization that is working to protect patient rights and end stigma against those who choose cannabis as medicine.

4. If you have side effects, stop or lower the dose

CBD won’t get you high the way that cannabis with THC can, but it may still cause side effects. “The most common side effects are fatigue and lethargy, and in rare cases diarrhea,” says Dr. Patel, who notes that CBD that’s taken topically less commonly causes side effects. Topical CBD is best used to address pain in a single joint, rather than widespread pain, she adds.

No matter which form of CBD you use, pay attention to how you feel. If you notice any negative side effects, stop or lower the dose and consult your doctor.

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Источник: https://creakyjoints.org/alternative-medicine/cbd-dosage-for-pain/

How to find the proper CBD dosage for you, according to medical cannabis experts

What Dosage of CBD Should You Take?

CBD is one of more than 60 active compounds found in the cannabis plant. It's used to treat childhood epilepsy, but is also being studied as a way to manage and treat conditions including anxiety, schizophrenia, diabetes , Parkinson's disease, and multiple sclerosis.

However, how much CBD you need for these conditions, or otherwise, is unclear. That's because CBD is not regulated by the FDA and therefore lacks any official dosing guidelines. 

That said, preliminary research provides a basic understanding of how much CBD can be effective for certain conditions and groups of people. Here's what researchers know so far about CBD's dosage and effects.

Important: Un THC — another common compound in marijuana — CBD is non-intoxicating and won't make you feel «high.» 

How to determine CBD dosage? 

Related What's the difference between CBD and THC? Understanding their health benefits and side effects

How much CBD you should take depends on multiple factors body weight and genetics. Usually finding the right dose comes down to good, old-fashioned trial and error. 

However, before experimenting with different CBD doses, you should talk to your doctor since there are no regulated dosing guidelines.

Plus, studies on CBD's effects include a wide range of doses, from «lower» doses of 10mg to 100 mg to «higher» doses of 100 mg to 1,500 mg, making it even more difficult to determine the proper dose on your own, says Anthony Ferrari, PhD, the Chief Science Officer of Your CBD Store, a nationwide CBD retail and research company. 

How much CBD is in a drop of CBD oil? CBD oil typically comes in dropper bottles with a single drop containing about 0.05 ml.

A product's packaging will tell you how much CBD is in the bottle, which can help you determine how much CBD is in a single drop.

For example, if a 20 ml bottle containing 2,000 mg of CBD contains 400 drops, then each drop would contain around 5 mg of CBD. 

Further muddling the dosing equation is the fact that some CBD products, known as isolates, contain only CBD, while others are «full-spectrum» and contain other cannabinoids, THC. The additional cannabinoids in full-spectrum formulas might modulate CBD's effects, thus altering how much you need to take, Ferrari says. 

Factors that influence how much CBD you should take include: 

  • Bodyweight: Studies examining CBD's effects use different doses depending on their body weight. These doses typically range from 5 to 20 mg per kilogram of body weight. 
  • The condition being treated: «The clinical trial data as it stands usually suggests a lower dosage for ailments such as anxiety and a higher dosage for ailments such as sleep, chronic pain, and epilepsy,» Ferrari says. 
  • Your individual body chemistry: Individuals respond differently to varying dosages of CBD due to their individual genetics and brain chemistry, says Jordan Tishler, MD, president of the Association of Cannabis Specialists and CEO of medical cannabis practice inahleMD. For example, a dose that might make one person feel slightly drowsy might cause unmanageable fatigue in another. 

CBD dosage conditions

Clinical trials on CBD are limited and existing studies use a wide range of doses to treat various conditions. Here's what we know so far: 

Anxiety 

Studies examining CBD's effects on anxiety use varying doses, typically ranging from 400 mg to 600 mg per day. In a small 2017 study, test subjects reported reduced anxiety after taking a 300 mg dose of CBD. 

Schizophrenia

In a couple of small studies, CBD doses ranging from 600 mg to 1500 mg per day were shown to reduce some symptoms of psychosis due to schizophrenia. 

Can you take too much CBD? 

CBD is generally considered to be safe and well-tolerated in doses up to 1500mg per day. While there's a real risk of fatal overdose when using drugs opiates or alcohol, taking too much CBD is more ly to result in sleepiness and perhaps an upset stomach.

Side effects are typically mild and include: 

  • Dry mouth
  • Drowsiness
  • Diarrhea 
  • Nausea

In rare instances, CBD could cause liver damage. A 2019 animal study found that liver damage occurred when mice were given high doses of CBD  — the human equivalent of 200 mg of CBD per kilogram of body weight. It's not clear if these findings are applicable to humans. 

Related Why you should never use weed during pregnancy even if it's an edible

«If you are pregnant, breastfeeding, or taking any other medications, you should discuss your CBD journey with a primary care physician, Ferrari says. «Everyone experiences the effects of CBD differently and you should always monitor your body's reactions.»

Warning:  Taking CBD in addition to other medications that cause drowsiness — benzodiazepines, antipsychotics, antidepressants, antihistamines, or alcohol — may lead to increased drowsiness, accidental falls, or accidents while driving. 

Insider's takeaway 

Emerging research suggests CBD is a promising and low-risk treatment for a number of conditions — but all medications, you need to be cognizant of dose. Because there are no regulated dosing guidelines, it's especially important to talk to your doctor before starting a CBD regime. 

«Maintaining open communication with your physician is the key to overall success when first incorporating CBD into your routine, especially for those with complicated health issues,» Ferrari says. 

Источник: https://www.insider.com/cbd-dosage

CBD Dosage: How Much Should You Take?

What Dosage of CBD Should You Take?

Cannabidiol (CBD) is growing increasingly popular, thanks to its many purported health benefits and non-psychoactive properties (most CBD products contain less than 0.3% tetrahydrocannabinol, or THC). As research evolves and sheds light on CBD’s efficacy, especially for pain relief, more and more people are adding it to their daily wellness regimens.

Consumers can choose from a variety of CBD products, from oils to gummies to vapes to capsules. But figuring out the safe and effective CBD dose for an individual is a complex decision.

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Here’s how to find the right CBD dosage for you and how to consume it safely.

With the exception of one CBD product, a prescription drug used to treat seizures associated with particular syndromes, the Food and Drug Administration (FDA) doesn’t regulate the use of CBD. (In fact, it’s illegal to market CBD as a supplement or add it to food.) Therefore, it’s best to consult a doctor with experience in CBD administration to determine your ideal dosage.

Expressed in milligrams (mg), CBD dosage largely depends on the conditions and symptoms you’re trying to treat and your unique endocannabinoid system, which is associated with motor control, behavior, emotions, the nervous system and homeostasis. CBD dosage remains an area of active research—more large, high-quality studies are needed in different populations to determine appropriate dosing, efficacy and safety guidelines.

“It’s best to start small and gradually increase your dose up to a level that gives you the desired effect,” says Cheryl Bugailiskis, M.D., a cannabis specialist at Heally, a telehealth platform for alternative medicine. Your starting point might look half a CBD gummy or a drop of oil. Ideally, navigate this process under the guidance of a qualified physician.

If you’re still not sure where to start, mydosage.com offers a questionnaire and CBD calculator to help you your specific symptoms and usage goals.

When you consume CBD gummies, capsules or softgels, dosage is typically expressed per unit. For example, there may be 50 milligrams of CBD in each individual gummy.

These products don’t offer much dosage flexibility since you can’t split up capsules easily.

For instance, if one softgel capsule didn’t provide your desired result, you would have to take another full capsule, doubling the total dose.

CBD oil, on the other hand, makes it easier, to begin with a small dose. But calculating CBD oil dosage can be less straightforward. Oils and tinctures tend to come in a dropper bottle and, typically, only the total liquid volume and CBD contents are listed on the label. For example, the label might simply state there’s 1,500 milligrams of CBD in the 30-milliliter bottle.

But what does 1 milliliter look ? Due to the current lack of regulation of CBD, this calculation can be tricky. Start by figuring out the volume of a single drop in your dropper, which is usually 0.05 milliliters, according to Dr. Bugailiskis. If you’re unsure, ask the company.

Here’s where math comes in. Let’s continue with the 30-milliliter bottle with 1,500 milligrams of CBD and 0.05 milliliters in a single drop as our example.

1500mg÷30mL = 50 mg/mL

This bottle contains 50 milligrams of CBD per milliliter. Let’s see how many milligrams are in a drop:

50mg/mL ×0.05mL/drop = 2.5mg/drop

Each drop contains 2.5 milligrams of CBD.

Next, you can calculate how many drops you need to reach your goal dosage. Let’s say you want to consume 25 milligrams each day.

25mg÷2.5mg/drop = 10 drops
10 drops ×2.5mg = 0.5mL

With this CBD oil dosage calculator as your guide, you would find that you needed to consume 10 drops, or 0.5 milliliters, to reach 25 milligrams. And if you intend to consume 25 milligrams daily, you can expect this particular bottle to serve as a 60-day supply.

Some CBD products do some of this math for you and illustrate how many milligrams are in a milliliter, some even marking these points on the dropper so you know exactly what you’re taking.

CBD Dosage for Different Ailments

Without FDA approval, there is little guidance in the U.S. on how much CBD a person should consume for various conditions.

In many medical studies on CBD, you see administered doses reach hundreds of milligrams a day, which sounds severe compared to our starting dosage example of 25 milligrams.

However, Steven Phan, founder of Come Back Daily, a CBD dispensary in New York, points out that patients in these studies are often dealing with serious flare-ups and pain-inducing conditions compared to everyday dispensary customers.

Below are clinically-studied CBD dosages different ailments and conditions. Note: Some of the formulations studied contained THC as well—not all available dosage research sticks strictly to CBD.

*Dosages are based solely on small, short-term clinical study results where CBD proved significantly successful over placebo. Much larger studies are needed to further strengthen the evidence.

FDA-approved Epidiolex administers CBD orally as a liquid to treat seizures associated with Lennox-Gastaut syndrome, Dravet syndrome and tuberous sclerosis complex. The dosage of Epidiolex is determined by taking the patient’s weight in kilograms (kg) into account.

Several countries, including Canada and those in the U.K., have approved the use of Sativex, an oral spray with equal amounts of CBD and THC, to treat pain stemming from multiple sclerosis. Canada has also approved it for treatment of cancer pain.

The medical and research community still has a long way to go before figuring out what dose works best for each condition. At an individual level, consumers can experiment with caution until they find what works best for them.

Popular ways to take CBD include:

  • Oils and tinctures (extracts of plant material dissolved in ethanol): A liquid that comes in a bottle with a dropper
  • Gummies: A soft, chewable candy that’s often fruit-flavored
  • Sprays: A liquid that comes in a bottle with a nozzle for spraying into the mouth
  • Capsules: Tablets or softgels that are ingested by mouth
  • Vapes: CBD oil that’s heated without ignition, resulting in an inhalable vapor
  • Flower: Dried hemp plant that’s often ignited and smoked
  • Edibles: Any food that CBD oil has been added to, such as brownies or chips
  • Drinks: Any beverage that’s infused with CBD, often in the form of hemp extract

Your CBD product of choice will largely depend on your personal preferences, as well as your budget since prices vary depending on the potency of ingredients and manufacturing processes.

Different mediums also offer varying levels of bioavailability—or how much of what you take is actually absorbed into your bloodstream to have an effect.

For example, if you ingest 10 milligrams of CBD via 1 milliliter of liquid, your body might absorb about 60% of it, or about 6 milligrams.

Cannabinoids generally have a low bioavailability compared to other substances, according to Jordan Tishler, M.D., a physician specializing in cannabis treatment in Massachusetts. However, “products that contain emulsifiers egg yolk (brownies) or lecithin (some gummies) do better,” he says.

With that said, ingesting CBD via gummies or other edibles may take longer to take effect since the CBD has to travel to your digestive system to be broken down and absorbed.

Can You Take Too Much CBD?

with any substance, you can take more CBD than your body can handle. Studies show doses up to 1,500 milligrams a day have been well-tolerated, but every person is different . Ingesting too much CBD can cause unpleasant side effects, such as dry mouth, nausea, diarrhea, upset stomach, drowsiness, lightheadedness and general disorientation. While rare, liver damage can also occur.

What’s more, CBD can have serious interactions with certain medications. In evaluating available information on five prescription CBD-based medications, researchers found 139 medications could have a potential drug-drug interaction with CBD. People who take certain blood thinners, heart rhythm medications, thyroid medications and seizure medications need to be particularly careful.

At the end of the day, not all supplements are created equal, which is why it’s important to work alongside a healthcare provider when adding CBD to your wellness regimen and research reliable brands. And while emerging research and anecdotal evidence is promising, more large, randomized-controlled trials are needed to further understand the benefits of CBD and its dosing.

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Источник: https://www.forbes.com/health/body/cbd-dosage/

CBD Dosage: How Much CBD Do I Take?

What Dosage of CBD Should You Take?

These days CBD can be found nearly anywhere in almost anything.

There are CBD lattes at the local café, an ever-growing array of beauty products, and CBD is even stacked on the shelves of pharmacy chains located across the U.S.

It's not hard to find CBD oil and CBD-infused products, but finding the most effective CBD dosage, on the other hand, well, that's an entirely different story.

CBD is a non-intoxicating cannabinoid from the cannabis plant that offers an extensive number of potential therapeutic benefits, including anti-inflammatory, analgesic, anti-anxiety, and seizure-suppressant properties.

Although its popularity had already started simmering, the CBD market shifted into a higher gear once hemp production was legalized with the passage of the 2018 Farm Bill.

This measure paved the way for a massive influx of hemp-derived CBD oil and CBD-infused products on the consumer market, but most users are still unaware of how to find the most effective CBD dosage.  

Evidence shows that CBD holds promise in treating a wide range of conditions and ailments.Photo by: Gina Coleman/Weedmaps

Although more research is needed in order to define the most effective CBD dosage for specific ailments and conditions, evidence shows that CBD holds promise in treating a wide range of conditions and ailments, including epilepsy, chronic pain, inflammation, opioid addiction, and anxiety, among others. 

Knowing the way that CBD products work and are marketed can improve one's ability to accurately administer CBD for specific ailments or conditions.

What to look for in CBD products

While sifting through the vast ocean of CBD oils and infusions now available online and in health and wellness sections across the US, it's important to know what to look for in order to find the best possible products.

What type of CBD product should you consider? 

There are a lot of different CBD products on the market, and each requires different considerations when it comes to the optimal CBD dosage. This diverse array of CBD product types includes: 

  • CBD oil
  • Topicals, such as creams and lotions
  • Capsules
  • Sublinguals, such as oral sprays and droppers
  • Edibles
  • Vape pens
  • High-CBD flower
  • Isolate
  • Suppositories

Certificate of analysis from third-party testing lab

First and foremost, it's highly important to find CBD oil or CBD-infused products from a reputable source, preferably one that includes a certificate of analysis from a third-party testing lab. By having third-party product verification, the amount of CBD inside the product, along with other potential ingredients, can be confirmed without solely relying on the manufacturer's word. 

The total amount of CBD and amount per serving size should always be clearly showcased on your product's label.Photo by: Gina Coleman/Weedmaps

Since the legalization of hemp-derived products via the 2018 Farm Bill, the Food and Drug Administration (FDA) has continued to grapple with how to regulate CBD oil and CBD-infused products. This lack of oversight has led to products that either contain less CBD than advertised or no CBD at all.

For instance, in a November 2017 study, researchers tested 84 CBD products from 31 companies. Only 30.95% of the samples were accurately labeled with the correct amount of CBD.

Read the product label

Aside from proof of third-party testing, there's additional information that should be listed on the label of the CBD products.

By knowing what to look for on CBD product labels, consumers have a better chance of finding high-quality items. The total amount of CBD and amount per serving size should always be clearly showcased on the label.

Look for the following details on CBD product labels to ensure that it comes from a reputable source: 

  • Amount of active CBD per serving 
  • Supplement Fact Panel, including other ingredients
  • Net weight
  • Manufacturer/Distributor name
  • Suggested Use
  • Full-spectrum, broad-spectrum, or isolate
  • Batch/date code
  • Expiration date

Don't fall prey to enticing buzzwords such as “organic' or “all-natural,” as they can be misleading and don't have a scientific basis. There are also some product labels that claim to contain hemp or hempseed oil, but this is not the same as hemp-derived CBD oil, and frequently contains little to no cannabinoids at all.

Know the CBD-to-THC ratio

It's also important to know whether the CBD product contains any THC and, if so, what the exact CBD-to-THC ratio is. The way this ratio works is relatively simple.

For instance, a CBD oil that claims to offer a 3:1 CBD-to-THC ratio will have around three times more CBD than THC.

The higher the amount of CBD, the more the consumer is protected from the undesirable effects of THC, such as anxiety and paranoia. 

The CBD-to-THC ratio can vary from product to product, but there are certain ratios that seem to be commonplace among most manufacturers, usually ranging anywhere between 1:1 and 18:1. A product with an 18:1 CBD-to-THC ratio provides the best chance for avoiding any semblance of the high that THC produces.

A product with a 1:1 CBD-to-THC ratio is more balanced, better suited for someone who is prepared for the intoxicating effects of THC, even if they are mild. Something in the mid-range, such as a 2:1 or 3:1 CBD-to-THC ratio, will be higher in CBD, but will still slightly maintain the sensory and psychoactive effects of THC.

Ultimately, however, a person's individual level of tolerance to THC's effects will affect their level of intoxication. 

CBD with THC work in tandem to create a more beneficial and therapeutic experience,Photo by: Gina Coleman/Weedmaps

Finding the most effective CBD dosage will ly require a bit of experimentation, but knowing how different CBD-to-THC ratios work can help narrow down the search. Start with a CBD product that has high levels of CBD and, if necessary, slowly transition to something that contains more THC. There is also a wide range of hemp-derived CBD on the market, which contains less than 0.3% to no THC.  

As for why you might want to combine CBD with THC in the first place, research suggests that the two cannabinoids work in tandem to create a more beneficial and therapeutic experience, often referred to as the entourage effect. 

One 2006 literature review published in Medical Hypothesis suggests that CBD can improve the therapeutic benefits and reduce the adverse effects of THC.

Other research appears to support the view that CBD and THC have a positive synergistic effect when combined. For instance a 2012 study found that cannabis consumers with a higher intake of CBD had better recall memory.

There is also evidence suggesting that CBD can reduce anxiety and paranoia, two side effects commonly associated with THC. 

Consider the ailment or condition

The optimal CBD dosage will not only depend on the individual, but also their ailment or condition. Depending on the therapeutic needs, different CBD products may prove more beneficial than others. 

For instance, to combat arthritis or chronic pain, a CBD-infused topical applied directly at the site of pain may be more effective than a sublingual oil or tincture.

In a 2016 study conducted on lab rats, researchers found that CBD had limited oral bioavailability, leading them to surmise that topical CBD may be more effective when it comes to treating inflammation or pain in a specific area, such as arthritis or muscular pain.

How much CBD oil should I take?

While further research and educational tools are required to pinpoint the optimal CBD dosage for each individual, existing studies can help narrow down the best CBD dosages for certain ailments and medical conditions. For instance, Mayo Clinic, the U.S.

-based nonprofit academic medical center, released a review that can be used as a starting point for THC and CBD dosage measurements for various ailments, combining scientific research, publications, and traditional and expert opinions. information in the review, it might be helpful to start with a dose of 2.

5 — 10mg of CBD to reduce anxiety or 160mg for inflammation.

Finding the ideal CBD dosage is dependent on several factors, including the individual's weight, diet, metabolism, other medications, genetics, and medical condition, as well as the formulation and quality of the CBD. Photo by: Gina Coleman/Weedmaps

But finding the ideal CBD dosage is dependent on several factors, including the individual's weight, diet, metabolism, other medications, genetics, and medical condition, as well as the formulation and quality of the CBD.

Therefore, it's not yet possible to develop universal CBD dosage guidelines that work effectively for everyone, but well-educated estimates can still be made using the limited information currently available.

Of course, novice users should start with a lower dose and work their way up until the optimal CBD dosage is found. 

When administering CBD oil, the corresponding dropper in the bottle can be used to obtain an accurate measurement. The right amount will be subject to the desired CBD dosage and product serving size.

For example, one 50-milliliter bottle contains 2,000 milligrams of CBD. Considering a standard dropper typically holds one milliliter of liquid, just divide the milligrams of CBD by the amount of liquid in the bottle.

In this case, one full dropper should contain 40 milligrams. 

So, to start with a CBD dosage of 20 milligrams, simply fill half of the dropper and administer the oil underneath the tongue. Holding under the tongue is a critical step in tincture consumption because CBD is very poorly absorbed by the gastrointestinal tract (i.e.

, very little of what is swallowed ends up in the bloodstream).

Efforts are underway to develop formulas that increase the oral bioavailability of CBD; these may include consuming it alongside piperine, a molecule found in black pepper, which is commonly used to boost the absorption of turmeric.

Lastly, it's always worth consulting a physician about using CBD to treat a specific medical condition or ailment. While medical professionals might not yet have clinical expertise regarding CBD, they may still be able to provide guidance on the optimal CBD dosage for each patient.

Источник: https://weedmaps.com/learn/cbd/a-guide-to-cbd-dosage

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