How Long Does Oxycodone Stay in Your System?

How Long Does Oxycodone Stay in Your System?

How Long Does Oxycodone Stay in Your System?

Depending on what type is taken, oxycodone will generally affect you for somewhere between 4 and 12 hours. Its use can usually be detected within three days on most drug tests.

Testing for Oxycodone

There are many reasons to test a person for oxycodone abuse. Generally, drug tests are given to employees to make sure they are not abusing drugs. 

When to test for drugs can be a hotly debated topic, but such testing clearly has some place in society. In some cases, it is very important that an organization’s members are not abusing drugs, especially while doing their job.

One particularly common example of drug testing is for opioid abuse. Most opioids can be detected in urine within 3 days and in hair within about 30 days of use. Toxicology, which drug testing falls under, is a complicated science, however.

In the case of oxycodone, there are some factors in play that need to be taken into account when determining how long it is going to affect you and how long the use will be detectable. 

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Duration of Effect

Oxycodone comes primarily in two forms. There is short-acting oxycodone Percocet, which lasts for about 4 to 6 hours. There is also long-lasting oxycodone Oxycontin, which lasts for about 12 hours. 

Multiple sources estimate that short-acting oxycodone has a half-life of around 3 to 4 hours, and long-lasting oxycodone has a half-life of about 12 hours. This is the point where the body has removed roughly half of the drug from the system, thus greatly diminishing its effects. 

This is only tangentially related to dependency. Oxycodone is a potentially very addictive opioid. 

You can be psychologically dependent on oxycodone. If you have grown physically dependent on it — as most abusers and even legitimate users will — you may go through serious withdrawal after stopping use. Consult a health care professional if you have concerns about being unable to stop opioid use. It’s not safe to stop use suddenly without medical assistance.

Oxycodone Detection

Detecting oxycodone specifically is actually a bit tricky, according to Premier Biotech, a company that specializes in drug testing. As numerous other drug testing labs will note, standard urine testing can easily miss oxycodone, primarily because a standard opioid urine test is searching for morphine and/or codeine use. 

Adjustments can be made to specifically test for oxycodone, however. The organization or individual ordering the test may have to request such an adjustment, potentially at additional cost. 

This is an important element for any organization that requires drug testing to remember. A standard drug test, even for a category of drugs, may not catch every drug in that category.

Timeline for Detection

When the test parameters are properly set, oxycodone is able to be detected roughly in line with how long most other opioids are detected. 

It can be detected in urine within about three days of use, and it can detected in hair, if the use was fairly chronic, within 30 to 90 days of use. 

There are a few factors that cause that window to be so large. Drug detection, especially in hair, is reliant on:

  • Frequency of use.
  • Potency or dose of the drug taken during those uses.
  • Length of hair. This is less an issue than it may seem. For example, Quest Diagnostics (a drug testing lab) requires 3.9 cm of hair to achieve an approximately 90-day history of drug use.
  • Length of time since last use (hence the windows of detection noted above).

Urine testing is the most popular choice for drug testing, at least for opioids. 

Blood tests are much more invasive and generally have comparable accuracy and time windows of detection to urine testing. 

Hair testing is not as invasive as you might imagine since only a small portion of hair is taken, but it cannot detect recent drug use.

Hair testing is therefore only really useful in proving chronic drug use. 

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Final Notes on Oxycodone Testing

While there are legitimate concerns about which organizations deserve to know about a person’s drug habits, if you are worried about your use of oxycodone being detected, it is ly a sign you have a problem with abuse. Oxycodone abuse can be incredibly destructive. If you think you have a problem with addiction, there is no shame in getting help.


How Long Does Oxycodone Stay In Your System?

How Long Does Oxycodone Stay in Your System?

The opioid epidemic has been a serious issue in the United States for several years. Overdoses from these drugs have risen dramatically and several people have become in need of opioid addiction treatment. One such drug that has been part of the problem is oxycodone.

What Is Oxycodone?

Oxycodone is a type of semisynthetic opioid used to treat pain. It can come in a variety of forms including immediate-release and extended-release tablets as well as different brand names. Percocet and Percodan both contain oxycodone and are immediate-release drugs. OxyContin is an extended-release form of oxycodone.

Although oxycodone has valid medical purposes and is prescribed by doctors, it can also be dangerous if abused. Oxycodone has a high propensity for dependence, so people often need formal oxycodone addiction treatment to safely stop misuse once they become addicted to the drug

How Long Does Oxycodone Stay in Your System?

Although the effects of the drug may wear off in a few hours, oxycodone may still be present in a person’s system for much longer. In some cases, traces of oxycodone may even be found months after it was last taken.

Just how long oxycodone stays in the body and its detection time will depend on a variety of factors and could be different for everyone. Generally, people who use oxycodone long-term or in heavier doses are more ly to have traces of this drug in their bodies for an extended time.

Oxycodone Drug Test Detection Times

Because traces of the drug can remain in the body long after the effects wear off, oxycodone can be detected by drug tests after the immediate high passes. The exact detection time of oxycodone can vary from person to person and will change several factors.

The oxycodone detection time may depend on:

  • Frequency of use
  • Dosage
  • Age of the user
  • Gender of the user
  • Diet of user
  • Weight of the user
  • Type of drug test

Arguably the biggest factor impacting the detection time of oxycodone is the type of drug test used. Different drug tests have different windows of detection and some are more accurate than others.

Urine Tests

Because they are noninvasive and easy to execute, urine tests are the most popular way to test for the presence of oxycodone in the body. Generally, the oxycodone detection time of urine is around two to four days.1

Blood Tests

While highly accurate, the oxycodone detection time for blood tests is shorter. Generally, oxycodone can only be detected in blood for about 24 hours after the last dose.2

Hair Tests

While not commonly used, hair samples have a much larger window of detection. The oxycodone detection time from a hair sample may extend as far back as 90 days.2

Saliva Tests

Saliva drug tests are also rare. Generally, these tests can detect opioids in the body oxycodone within the last 50 hours.2

Oxycodone Metabolism & Half-Life

Whether or not oxycodone is detected in a drug test not only depends on the window of detection time of the test itself but also largely on how oxycodone is metabolized. After ingestion, oxycodone is processed through the digestive system and is broken down in the liver. Most of the leftover metabolites are then excreted in the urine.3

The half-life of a drug refers to the amount of time it takes the body to metabolism half of the amount of the substance ingested. Generally, an oral dose of oxycodone has a half-life anywhere from 2.5 to 4 hours.

3 The half-life and metabolic rate of oxycodone can be impacted by several factors including the frequency of use, route of administration, and dosage of the drug as well as a person’s gender, age, diet, and weight.

Regular abuse may lead to a longer oxycodone detection timeline, and different routes of administration tend to have different metabolic rates because of the way the body initially processes the drug. Also, if larger amounts of oxycodone were ingested, traces of the drug will most ly be detectable in the body for a longer period of time.

The metabolic rate of oxycodone may also be impacted by individual differences. Younger users tend to have faster metabolisms in general and may be able to metabolize oxycodone at a faster rate.

Women are also believed to eliminate oxycodone 25% slower than men.

3 Those with a higher body fat ratio may retain oxycodone for longer periods of time, and food and water intake could also impact how quickly the body can process the drug.

Get Help

When opioid abuse continues, it can lead to serious consequences for the user as well as their families. At Vertava Health Ohio, formerly The Bluffs, we want to help. Because Ohio is a state with one of the highest rates of opioid overdoses, we understand just how dangerous these drugs can be and have witnessed their destruction firsthand.

With programs tailored to patients’ unique needs, our Ohio drug rehab is here to help you or your loved one safely overcome these addictions and move forward with your lives. Contact us today to learn more.

We can help you overcome addiction and get your life back. Your calls are always free and 100% confidential.



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